JWH-018, also known as AM-678, is a synthetic cannabinoid that was first synthesized in the 1990s by John W. Huffman. It is a potent agonist of the CB1 receptor and is commonly used as a research chemical. Due to its psychoactive effects, JWH-018 has gained popularity in certain circles as a recreational drug. However, it is important to note that the sale and consumption of JWH-018 may be illegal in some jurisdictions.

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